Distinct Genealogies for Plasmids and Chromosome
نویسندگان
چکیده
An earlier perspective on the diversity of conjugative elements in microbes [1] attempted to provide a broad audience with an introductory overview of the arcane biology of mobile genetic elements and their terminologies. It might well have been entitled ‘‘Plasmids, ICEs, IMEs, and Other Mobile Elements for Dummies,’’ but common sense prevailed. This perspective introduces two related articles in the current issue of PLOS Genetics [2,3] and might have equally aptly been entitled ‘‘Antibiotic-Resistant Plasmids and Their Epidemiology for Dummies.’’
منابع مشابه
Detection of Plasmids in Heavy Metal Resistance Bacteria Isolated from the Persian Gulf and Enclosed Industrial Areas
Several heavy metal resistant bacterial strains were isolated from sediment and water samples collected from the Persian Gulf and enclosed industrial areas. All the isolated bacteria were identified by 16S rRNA gene sequencing. Isolated bacteria were tested for the presence of plasmids using the modified alkaline lysate method. The method was effective for identification and characterization of...
متن کاملDevelopment of an Alu-PCR Amplified YAC Probe Suitable for Enumeration of Chromosome 13 on Uncultured Lymphocytes and Amniocytes by Fluorescence in situ Hybridization
The main objective of the present study was to develop an efficient and reliable probe to be routinely used for detection of chromosome 13 copy numbers by interphase FISH. To achieve this, a Yeast Artificial Chromosome (YAC) containing sequences specific for human 13q12 (744D11), was cultured and the whole yeast genomic DNA was extracted. The human insert within the isolated DNA was amplified b...
متن کاملJenti: an efficient tool for mining complex inbred genealogies
SUMMARY An efficient tool for mining complex inbred genealogies that identify clusters of individuals sharing the same expected amount of relatedness is described. Additionally it allows for the reconstruction of sub-pedigrees suitable for genetic mapping in a systematic way. AVAILABILITY http://www.jenti.org.
متن کاملImprecise excision of plasmid pE194 from the chromosomes of Bacillus subtilis pE194 insertion strains.
Plasmid pE194 has been shown to be rescued by integration after cultivation of infected Bacillus subtilis recE4 cells at a restrictive high temperature. The plasmid is also spontaneously excised from the chromosome at a low frequency by precise or imprecise excision (J. Hofemeister, M. Israeli-Reches, and D. Dubnau, Mol. Gen. Genet. 189:58-68, 1983). We have investigated nine excision plasmids,...
متن کاملPurifying selection causes widespread distortions of genealogical structure on the human X chromosome.
The extent to which selective forces shape patterns of genetic and genealogical variation is unknown in many species. Recent theoretical models have suggested that even relatively weak purifying selection may produce significant distortions in gene genealogies, but few studies have sought to quantify this effect in humans. Here, we employ a reconstruction method based on the ancestral recombina...
متن کامل